| Perspectives |
| Gynecology, STD, Cervix Diseases, Vaccines, Neoplasms |
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HPV infections: Can they be eradicated using nanotechnology?
18 November 2011
Abstract: Human papillomavirus (HPV) infections are considered the most common sexually transmitted diseases, with more than 450 million people worldwide infected. HPVs can cause anogenital warts and ...
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Marianna Foldvari
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131-135
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| Feature Article |
| Pathology, Neoplasms, Metastasis Inhibition, Metallofullerenes |
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Gadolinium metallofullerenol nanoparticles inhibit cancer metastasis through matrix metalloproteinase inhibition: imprisoning instead of poisoning cancer cells
19 September 2011
Abstract: The purpose of this work is to study the antimetastasis activity of gadolinium metallofullerenol nanoparticles (f-NPs) in malignant and invasive human breast cancer models. We demonstrated t...
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Huan Meng,
Gengmei Xing,
Elvin Blanco,
Yan Song,
Lina Zhao,
Baoyun Sun,
Xiaoda Li,
Paul C. Wang,
Alexandru Korotcov,
Wei Li,
Xing-Jie Liang,
Chunying Chen,
Hui Yuan,
Feng Zhao,
Zhen Chen,
Tong Sun,
Zhifang Chai,
Mauro Ferrari,
Yuliang Zhao
et al.
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136-146
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| Review Article |
| Pharmacology, Drug Delivery Systems, Nanoparticulates |
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Author(s) |
Pages |
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Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging
09 June 2011
Abstract: Drug delivery is an interdisciplinary and independent field of research and is gaining the attention of pharmaceutical researchers, medical doctors and industry. A safe and targeted drug del...
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Suphiya Parveen,
Ranjita Misra,
Sanjeeb K. Sahoo
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147-166
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| Research Articles |
| Cell Biology and Genetics, Gene Transfer, Modified PEI NPs |
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Author(s) |
Pages |
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Linear PEI nanoparticles: efficient pDNA/siRNA carriers in vitro and in vivo
16 June 2011
Abstract: Linear polyethylenimine (lPEI, 25 kDa) nanoparticles' (LPN) series was synthesized by varying percentage of cross-linking with 1,4-butanediol diglycidyl ether (BDE) and their size, surface c...
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Ritu Goyal,
Sushil K. Tripathi,
Shilpa Tyagi,
Anurag Sharma,
K. Ravi Ram,
Debapratim K. Chowdhuri,
Yogeshwar Shukla,
P. Kumar,
Kailash C. Gupta
et al.
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167-175
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| Immunology, Hypersensitivity, Complement Activation, Liposomes, CARPA |
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Pages |
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Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome
27 June 2011
Abstract: Hypersensitivity reactions to liposomal drugs, often observed with Doxil and AmBisome, can arise from activation of the complement (C) system by phospholipid bilayers. To understand the mech...
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János Szebeni,
Péter Bedőcs,
Zoltán Rozsnyay,
Zsóka Weiszhár,
Rudolf Urbanics,
László Rosivall,
Rivka Cohen,
Olga Garbuzenko,
György Báthori,
Miklós Tóth,
Rolf Bünger,
Yechezkel Barenholz
et al.
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176-184
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| Pharmacology, Neoplasms, MDR, Formulation, Pharmacokinetics, Hybrid Lipid-Dextran Carrier |
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Author(s) |
Pages |
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Novel nanostructured lipid-dextran sulfate hybrid carriers overcome tumor multidrug resistance of mitoxantrone hydrochloride
27 June 2011
Abstract: Novel nanostructured lipid-dextran sulfate hybrid carriers (NLDCs) were successfully developed for sustained delivery of water-soluble cationic mitoxantrone hydrochloride (MTO) and overcomin...
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Peng Zhang,
Guixia Ling,
Xiaolei Pan,
Jin Sun,
Tianhong Zhang,
Xiaohui Pu,
Shiliang Yin,
Zhonggui He
et al.
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185-193
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| Pharmacology, Neoplasms, Formulation, Pharmacokinetics, Hybrid Lipid-Dextran Carrier, Paclitaxel, RGD, Self-Assembly |
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Pages |
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A novel dextran-oleate-cRGDfK conjugate for self-assembly of nanodrug
27 June 2011
Abstract: We report a novel synthetic biocompatible material: a conjugate with a fatty acid-substituted dextran decorated with cRGDfK peptide, which was used as a stable coating material instead of th...
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Zhe Wang,
Ting Yee Lee,
Paul C. Ho
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194-203
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| Pharmacology, Neoplasms, MDR, Formulation, Pharmacokinetics, Doxorubicin, Gold NPs |
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Author(s) |
Pages |
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Gold-doxorubicin nanoconjugates for overcoming multidrug resistance
27 June 2011
Abstract: Multidrug resistance (MDR) is a major clinical obstacle to the success of cancer chemotherapy. Here we developed a gold-doxorubicin (DOX) nanoconjugates system to overcome MDR. Gold nanopart...
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Yan-Juan Gu,
Jinping Cheng,
Cornelia Wing-Yin Man,
Wing-Tak Wong,
Shuk Han Cheng
et al.
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204-211
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| Pharmacology, Oncology, Drug Delivery, Mesoporous Silica NPs, Camptothecin |
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Article Title |
Author(s) |
Pages |
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In vivo tumor suppression efficacy of mesoporous silica nanoparticles-based drug-delivery system: enhanced efficacy by folate modification
16 June 2011
Abstract: Mesoporous silica nanoparticles (MSNs) have proven to be promising vehicles for drug delivery. However, despite the potential, few studies have extended the success of in vitro studies to an...
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Jie Lu,
Zongxi Li,
Jeffrey I. Zink,
Fuyuhiko Tamanoi
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212-220
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| Endocrine System, Diabetes, Insulin, Intraepidermal Delivery Technology |
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Article Title |
Author(s) |
Pages |
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Simultaneous basal-bolus delivery of fast-acting insulin and its significance in diabetes management
16 June 2011
Abstract: Insulin delivery relies on subcutaneous or intravascular injection, leading to reduced patient compliance. Transdermal delivery of insulin has been successfully demonstrated but dose accurac...
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Guangjiong Qin,
Yunhua Gao,
Yan Wu,
Suohui Zhang,
Yuqin Qiu,
Fang Li,
Bai Xu
et al.
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221-227
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| Radiology, Diagnostic Imaging, Oncology, Fluorescence Imaging, Image-Guided Surgery |
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Author(s) |
Pages |
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In vivo cancer imaging by poly(ethylene glycol)-b-poly(ɛ-caprolactone) micelles containing a near-infrared probe
27 June 2011
Abstract: Noninvasive near-infrared (NIR) fluorescence imaging is a promising technique for the intraoperative assessment of solid tumor removal. We incorporated a lipophilic NIR probe, 1,1′-dioctadec...
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Hyunah Cho,
Guilherme L. Indig,
Jamey Weichert,
Ho-Chul Shin,
Glen S. Kwon
et al.
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228-236
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| Dermatology, Hypertension, Transdermal Nano-Delivery, Liposomes |
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Article Title |
Author(s) |
Pages |
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Formulation and optimization of nanotransfersomes using experimental design technique for accentuated transdermal delivery of valsartan
27 June 2011
Abstract: The purpose of this work was to develop and statistically optimize nanotransfersomes for enhanced transdermal of valsartan vis-à-vis traditional liposomes. Nanotransfersomes bearing valsarta...
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Abdul Ahad,
Mohammed Aqil,
Kanchan Kohli,
Yasmin Sultana,
Mohammed Mujeeb,
Asgar Ali
et al.
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237-249
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| Geriatrics, Chronic Disease, Dementia, Formulation, Chitosan-Coated PLGA NPs |
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Chitosan enhances the stability and targeting of immuno-nanovehicles to cerebro-vascular deposits of Alzheimer's disease amyloid protein
27 June 2011
Abstract: Alzheimer's disease amyloid β (Aβ) proteins accumulate in the cerebral vasculature and cause cerebral amyloid angiopathy (CAA). The objective of this study was to resolve critical formulatio...
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Kristen M. Jaruszewski,
Subramanian Ramakrishnan,
Joseph F. Poduslo,
Karunya K. Kandimalla
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250-260
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| Frontmatter |
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Cover
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A1
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About the Cover
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A2
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Editorial Board
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A3
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Table of Contents
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A4-A5
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